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Гастроэнтерология (анг,рус)

Methodological Instruction to Lesson № 6.



Hours: 5.

Working place: classroom, hospital wards.



1.     Give the definition of ulcerative colitis.

2.     Give the definition of Crohn’s disease.

3.     Name main groups of drugs to treat patients with ulcerative colitis.

4.     Name main groups of drugs to treat patients with Crohn’s disease.

5.     Name formulations (drugs) of 5-aminosalicylic acid.

6.     What can you say about sulfasalazine.

7.     Name side-effects of sulfapyridine.

8.     In which percent of patients side-effects of sulfasalazine are developed?

9.     How many mg of 5-aminosalicylic acid is in 1g of sulfasalazine?

10.                       What can you say about oral mesalamine agent?

11.                       What can you say about olsalazine?

12.                       What can you say about topical mesalamine?

13.                       Name advantages of topical mesalamine.

14.                       What can you say about corticosteroids?

15.                       Name side-effects of corticosteroids.

16.                       What can you say about mercaptopurine and azatioprine?

17.                       Name side-effects of mercaptopurine.

18.                       How often should be obtained complete blood count if patient take mercaptopurine?

19.                       Give essentials of diagnosis Crohn’s disease.

20.                       Name involvement localization in patient with Crohn’s disease.

21.                       Name differences between Crohn’s disease and ulcerative colitis.

22.                       Clinical presentation in patient with Crohn’s disease.

23.                       Name causes of intestinal obstruction.

24.                       Name symptoms in patient with intestinal obstruction.

25.                       Where can be enterocutaneous fistulas?

26.                       Why patients with Crohn’s disease often have gallstones?

27.                       Name changes in laboratory findings and there causes.

28.                       Name advantages of colonoscopy.

29.                       What can you see by colonoscopy?

30.                       How can you confirm the diagnosis Crohn’s disease?

31.                       Name complications of Crohn’s disease.

32.                       How can you confirm abscess and its clinical picture, treatment?

33.                       Name causes of obstructions. Treatment.

34.                       Name treatment of fistulas.

35.                       Treatment of perianal disease.

36.                       Differential diagnosis in patient with Crohn’s disease.

37.                       Name aims of the treatment of Crohn’s disease.

38.                       Name indication to TPN.

39.                       How will you decrease dosage of prednisolon.

40.                       Name topically active steroid.

41.                       If there is palpable inflammatory bowel mass how will you prescribe steroids?

42.                       Name indications to prescriptions immunomodulatory drugs.

43.                       Name drugs and dosage to maintaince of Crohn’s disease remissions.

44.                       Name indications for surgery.

45.                       Give essentials of diagnosis ulcerative colitis.

46.                       Name involvement localization in patient with ulcerative colitis.

47.                       Give classification and main doctors questions to patients with ulcerative colitis.

48.                       Physical examination in patients with ulcerative colitis.

49.                       Give characteristic to mild and moderate ulcerative colitis disease and their differences.

50.                       Name extracolonic manifestation in patients with ulcerative colitis.

51.                       What can you see by endoscopy in patients with ulcerative colitis?

52.                       Differential diagnosis in patient with ulcerative colitis.

53.                       Name treatment in patient with distal colitis.

54.                       Name treatment in patient with mild and moderate colitis.

55.                       Name treatment in patient with severe colitis.

56.                       What can you say about complications of ulcerative colitis?

57.                       Indications to surgery intervention in patient with ulcerative colitis.




1.     Therapy: Manual. The course of lectures/V. M. Fedosyeyeva, A. A. Chrenov. – Simferopol, 2003. – 94-111 p.

2.     Davidson’s Principles and practice of medicine (nineteenth edition)/Christopher Haslett, Edvin R. Chilvers and others. – Edinburgh, 2002. – 808-819 p.

3.     The Merck Manual of Diagnosis and Therapy (seventeenth Edition)/ Robert Berkow, Andrew J. Fletcher and others. – published by Merck Research Laboratories, 1999.

4.     Harrisons Principle if internal medicine (seventeenth Edition)/Fauci, Braunwald, Hasper and other. – Part 13, section 1, Chapter 289.


Prepared by Orlovsky A. V., assistant, c. m. s.,

                    Murenets N. A., postgraduate