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Гастроэнтерология (анг,рус)

Methodological Instruction to Lesson № 2.



Hours: 5.

Working place: classroom, hospital wards.



1.     Name anatomico-physiological peculiarities of esophagus.

2.     Name etiology of gastro-esophageal reflux disease.

3.     Why does hiatus hernia cause reflux?

4.     Name important features of hiatus hernia.

5.     Why do defective esophageal clearance and gastric contents cause reflux?

6.     Which patients have increased intra-abdominal pressure?

7.     Name dietary factors which can cause gastro-esophageal reflux?

8.     Clinical picture in patients with gastro-esophageal reflux disease.

9.     Name complications in patients with gastro-esophageal reflux disease.

10.                       Barret esophagus: definition, epidemiology, clinical presentation, diagnosis, management.

11.                       Benign esophageal stricture: etiology, clinical picture, diagnosis, management.

12.                       Investigations in patients with gastro-esophageal reflux disease.

13.                       Name indications to endoscopy in patients with suspected gastro-esophageal reflux disease.

14.                       What can you see by endoscopy in patients with gastro-esophageal reflux disease.

15.                       Which pH is diagnostic of reflux disease?

16.                       Name pieces of advice in patients with gastro-esophageal reflux disease.

17.                       Antacids: drugs with dosing regimen, side effects.

18.                       Name Histamin H2-receptor antagonists drugs with dosing regimen.

19.                       Name Proton-pump inhibitors with dosing regimen.

20.                       Step-down approach to treatment in patients with gastro-esophageal reflux disease.

Tests “GERD”

  1. Name main symptom in patients with gastro-esophageal reflux disease:
  1. Pain in the epigastrium
  2. Heartburn
  3. Nausea
  4. Vomiting
  1. Name cause of gastro-esophageal reflux disease, except:
  1. Hiatus hernia
  2. Dietary and environmental factors
  3. Weight loss
  4. Increased intra-abdominal pressure
  5. Weight gain
  1. What is Barret`s esophagus?
  1. pre-malignant glandular metaplasia of the lower esophagus
  2. this is a cancer of esophagus
  3. it can be redness, bleeding ulceration with stricture formation in esophagus
  4. it is an adenocarcinoma of stomach
  1. Which therapy can induce regression of Barret`s esophagus?
  1. acid suppression therapy
  2. antireflux surgery
  3. endoscopic ablation therapy or photodynamic therapy



    1. B; 2. C; 3. A; 4. C;




1.     Harrison’s Principles of internal medicine (17th Edition)/Fauci, Braunwald, Hasper and others. – Part 13, section 1, Chapter 286.

2.     Davidson’s Principles and practice of medicine (nineteenth edition)/Christopher Haslett, Edvin R. Chilvers and others. – Edinburgh, 2002. – 775-778p.


Prepared by Orlovsky A. V., assistant, c. m. s.,

                    Murenets N. A., postgraduate